THE WISCONSIN CARD SORTING TEST DISCRIMINATES SCHIZOPHRENIC-PATIENTS AND THEIR SIBLINGS

被引：33

作者：

SCARONE, S ^{[1
]}

ABBRUZZESE, M ^{[1
]}

GAMBINI, O ^{[1
]}

机构：

[1] UNIV MILAN,SCH MED,DEPT BIOMED & TECHNOL SCI,PSYCHIAT BRANCH,I-20133 MILAN,ITALY

来源：

SCHIZOPHRENIA RESEARCH | 1993年 / 10卷 / 02期

关键词：

RELATIVES OF SCHIZOPHRENICS; NEUROPSYCHOLOGY; WISCONSIN CARD SORTING TEST;

D O I：

10.1016/0920-9964(93)90044-J

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The following report is an evaluation of the performances of 35 schizophrenic patients and 35 of their siblings on the Wisconsin Card Sorting Test (WCST), a neuropsychological test considered sensitive to frontal lobe functioning. Thirty five normal subjects matched for age and education were the comparison group. The purpose of this study was to examine the relationship of the neurofunctional basis for schizophrenia to its familiar occurrence. Non-schizophrenic siblings of schizophrenic patients did not perform significantly different from normal subjects on the WCST; however, schizophrenic patients performed significantly worse than both their siblings and normal subjects. These results indicate that WCST dysfunction seems to be a characteristic related to the presence of the disease and that non-genetic factors could contribute to the WCST pathological profile.

引用

页码：103 / 107

页数：5