GLUTAMINE SYNTHESIS IS A REGULATORY SIGNAL CONTROLLING GLUCOSE CATABOLISM IN SACCHAROMYCES-CEREVISIAE

被引:6
作者
FLORESSAMANIEGO, B [1 ]
OLIVERA, H [1 ]
GONZALEZ, A [1 ]
机构
[1] UNIV NACL AUTONOMA MEXICO,INST FISIOL CELULAR,DEPT MICROBIOL,MEXICO CITY 04510,DF,MEXICO
关键词
D O I
10.1128/JB.175.23.7705-7706.1993
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The effect of glutamine biosynthesis and degradation on glucose catabolism in Saccharomyces cerevisiae was studied. A wild-type strain and mutants altered in glutamine biosynthesis and degradation were analyzed. Cells having low levels of glutamine synthetase activity showed high ATP/ADP ratios and a diminished rate of glucose metabolism. It is proposed that glutamine biosynthesis plays a role in the regulation of glucose catabolism.
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页码:7705 / 7706
页数:2
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