CLONING OF THE GENE ENCODING HUMAN SOMATOSTATIN RECEPTOR 2 - SEQUENCE-ANALYSIS OF THE 5'-FLANKING PROMOTER REGION

被引：23

作者：

GREENWOOD, MT

ROBERTSON, LA

PATEL, YC

机构：

[1] MCGILL UNIV,ROYAL VICTORIA HOSP,DEPT MED,FRASER LABS,MONTREAL,PQ H3A 1A1,CANADA

[2] MCGILL UNIV,ROYAL VICTORIA HOSP,DEPT NEUROL,MONTREAL,PQ H3A 1A1,CANADA

[3] MCGILL UNIV,ROYAL VICTORIA HOSP,DEPT NEUROSURG,MONTREAL,PQ H3A 1A1,CANADA

来源：

GENE | 1995年 / 159卷 / 02期

关键词：

G-PROTEIN COUPLED RECEPTOR; G+C-RICH; GENE EXPRESSION; GENOMIC CLONE;

D O I：

10.1016/0378-1119(95)00059-F

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Using a cDNA probe, genomic clones were obtained for the 5' flanking promoter sequence of the human somatostatin receptor 2-encoding gene (SSTR2). A 3.8-kb sequence directly upstream from the start codon was analyzed. This sequence shares a number of characteristics with the promoters of other G-protein-coupled receptor (GPCR)-encoding genes including a number of G+C-rich regions, binding sites for several transcriptional factors, and the absence of coupled TATAA and CAAT sequences.

引用

页码：291 / 292

页数：2

共 12 条

[1] THE SYNAPTOPHYSIN-ENCODING GENE IN RAT AND MAN IS SPECIFICALLY TRANSCRIBED IN NEUROENDOCRINE CELLS [J].