THE EXPANDING ROLE OF QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS (QSAR) IN TOXICOLOGY

被引：145

作者：

HANSCH, C

HOEKMAN, D

LEO, A

ZHANG, LT

LI, P

机构：

[1] Chemistry Department, Pomona College, Claremont

来源：

TOXICOLOGY LETTERS | 1995年 / 79卷 / 1-3期

关键词：

QSAR; CYTOCHROME P-450 INDUCTION; MUTAGENICITY;

D O I：

10.1016/0378-4274(95)03356-P

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

Quantitative structure-activity relationships (QSAR) have found wide use in correlating the bioactivity of all kinds of organic compounds with all kinds of biological entities. So many QSAR have been published that it is time for a new phase of study, that of comparative QSAR. From our current database of about 6000 QSAR illustrative examples are discussed.

引用

页码：45 / 53

页数：9

共 11 条

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