METABOLISM OF THE AROMATASE INHIBITOR 4-HYDROXYANDROSTENEDIONE INVIVO - IDENTIFICATION OF THE GLUCURONIDE AS A MAJOR URINARY METABOLITE IN PATIENTS AND BILIARY METABOLITE IN THE RAT

被引：47

作者：

GOSS, PE

JARMAN, M

WILKINSON, JR

COOMBES, RC

机构：

[1] INST CANC RES,DRUG DEV SECT,SUTTON SM2 5PX,SURREY,ENGLAND

[2] LUDWIG INST CANC RES,SUTTON SM2 5PX,SURREY,ENGLAND

来源：

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY | 1986年 / 24卷 / 02期

关键词：

D O I：

10.1016/0022-4731(86)90128-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：619 / 622

页数：4

共 14 条

[1] INACTIVATION OF AROMATASE INVITRO BY 4-HYDROXY-4-ANDROSTENE-3, 17-DIONE AND 4-ACETOXY-4-ANDROSTENE-3, 17-DIONE AND SUSTAINED EFFECTS INVIVO
BRODIE, AMH
GARRETT, WM
HENDRICKSON, JR
TSAIMORRIS, CH
MARCOTTE, PA
ROBINSON, CH
[J]. STEROIDS, 1981, 38 (06) : 693 - 702
[2] INHIBITION OF PERIPHERAL AROMATIZATION BY AROMATASE INHIBITORS, 4-HYDROXY-ANDROSTENE-3,17-DIONE AND 4-ACETOXY-ANDROSTENE-3,17-DIONE
BRODIE, AMH
LONGCOPE, C
[J]. ENDOCRINOLOGY, 1980, 106 (01) : 19 - 21
[3] EFFECT OF AN AROMATASE INHIBITOR, 4-HYDROXY-4-ANDROSTENE-3,17-DIONE, ON ESTROGEN-DEPENDENT PROCESSES IN REPRODUCTION AND BREAST-CANCER
BRODIE, AMH
SCHWARZEL, WC
SHAIKH, AA
BRODIE, HJ
[J]. ENDOCRINOLOGY, 1977, 100 (06) : 1684 - 1695
[4] STUDIES ON MECHANISM OF ESTROGEN BIOSYNTHESIS IN RAT OVARY .1.
BRODIE, AMH
SCHWARZEL, WC
BRODIE, HJ
[J]. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1976, 7 (10) : 787 - 793
[5] 4-HYDROXYANDROSTENEDIONE IN TREATMENT OF POSTMENOPAUSAL PATIENTS WITH ADVANCED BREAST-CANCER
COOMBES, RC
GOSS, P
DOWSETT, M
GAZET, JC
BRODIE, A
[J]. LANCET, 1984, 2 (8414) : 1237 - 1239
[6] FOSTER AB, 1986, J STEROID BIOCH, V24
[7] SPECIES VARIATIONS IN THRESHOLD MOLECULAR-WEIGHT FACTOR FOR BILIARY-EXCRETION OF ORGANIC ANIONS
HIROM, PC
SMITH, RL
WILLIAMS, RT
MILLBURN, P
[J]. BIOCHEMICAL JOURNAL, 1972, 129 (05) : 1071 - &
[8] JARMAN M, 1985, J CHEM RES, P114
[9] METABOLISM OF AMINOGLUTETHIMIDE IN HUMANS - IDENTIFICATION OF HYDROXYLAMINOGLUTETHIMIDE AS AN INDUCED METABOLITE
JARMAN, M
FOSTER, AB
GOSS, PE
GRIGGS, LJ
HOWE, I
COOMBES, RC
[J]. BIOMEDICAL MASS SPECTROMETRY, 1983, 10 (11): : 620 - 625
[10] JARMAN M, 1985, J CHEM RES M, P1301

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