MITOGENIC ACTIVITY AND RECEPTOR REACTIVITY OF HYBRID MOLECULES CONTAINING PORTIONS OF THE INSULIN-LIKE GROWTH FACTOR-I (IGF-I), IGF-II, AND INSULIN MOLECULES

被引：19

作者：

DEVROEDE, MA

RECHLER, MM

NISSLEY, SP

OGAWA, H

JOSHI, S

BURKE, GT

KATSOYANNIS, PG

机构：

[1] NIADDKD,MOLEC CELLULAR & NUTR ENDOCRINOL BRANCH,BETHESDA,MD 20205

[2] NICHHD,DEV ENDOCRINOL BRANCH,BETHESDA,MD 20205

[3] NCI,METAB BRANCH,BETHESDA,MD 20205

[4] CUNY MT SINAI SCH MED,DEPT BIOCHEM,NEW YORK,NY 10029

来源：

DIABETES | 1986年 / 35卷 / 03期

关键词：

D O I：

10.2337/diabetes.35.3.355

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：355 / 361

页数：7

共 46 条

[21] INSULIN AS A POTENT, SPECIFIC GROWTH-FACTOR IN A RAT HEPATOMA-CELL LINE [J].

KOONTZ, JW ;

IWAHASHI, M .

SCIENCE, 1981, 211 (4485) :947-949

[22]

MASSAGUE J, 1982, J BIOL CHEM, V257, P3958

[23]

MASSAGUE J, 1982, J BIOL CHEM, V257, P5038

[24] INSULIN PROMOTES THE GROWTH OF F9 EMBRYONAL CARCINOMA-CELLS APPARENTLY BY ACTING THROUGH ITS OWN RECEPTOR [J].

NAGARAJAN, L ;

ANDERSON, WB .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1982, 106 (03) :974-980

[25] PROINSULIN BINDS TO A GROWTH PEPTIDE RECEPTOR AND STIMULATES DNA-SYNTHESIS IN CHICK-EMBRYO FIBROBLASTS [J].

NISSLEY, SP ;

RECHLER, MM ;

MOSES, AC ;

SHORT, PA ;

PODSKALNY, JM .

ENDOCRINOLOGY, 1977, 101 (03) :708-716

[26]

NISSLEY SP, 1984, CLIN ENDOCRINOL META, V13, P43

[27] SYNTHESIS AND BIOLOGICAL EVALUATION OF A MODIFIED INSULIN INCORPORATING THE COOH-TERMINAL HEXAPEPTIDE (D-REGION) OF INSULIN-LIKE GROWTH FACTOR-II [J].

OGAWA, H ;

BURKE, GT ;

KATSOYANNIS, PG .

JOURNAL OF PROTEIN CHEMISTRY, 1984, 3 (04) :327-348

[28] A MODEL OF CELL-CYCLE CONTROL - SEQUENTIAL EVENTS REGULATED BY GROWTH-FACTORS [J].

OKEEFE, EJ ;

PLEDGER, WJ .

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1983, 31 (2-3) :167-186

[29] INSULIN AND MULTIPLICATION STIMULATING ACTIVITY (AN INSULIN-LIKE GROWTH-FACTOR) STIMULATE ISLET BETA-CELL REPLICATION IN NEONATAL RAT PANCREATIC MONOLAYER-CULTURES [J].

RABINOVITCH, A ;

QUIGLEY, C ;

RUSSELL, T ;

PATEL, Y ;

MINTZ, DH .

DIABETES, 1982, 31 (02) :160-164

[30] INTERACTION OF MULTIPLICATION-STIMULATING ACTIVITY WITH CHICK-EMBRYO FIBROBLASTS DEMONSTRATES A GROWTH RECEPTOR [J].

RECHLER, MM ;

PODSKALNY, JM ;

NISSLEY, SP .

NATURE, 1976, 259 (5539) :134-136

← 1 2 3 4 5 →