APPLICATION OF CAPILLARY ELECTROPHORESIS TO THE QUALITY-CONTROL OF PHARMACEUTICAL FORMULATIONS - EFFECT OF AREA CORRECTION ON QUANTITATION OF ANTITUSSIVES

被引:9
作者
KORMAN, M [1 ]
VINDEVOGEL, J [1 ]
SANDRA, P [1 ]
机构
[1] STATE UNIV GHENT,DEPT ORGAN CHEM,KRIJGSLAAN 281 S4,B-9000 GHENT,BELGIUM
关键词
CAPILLARY ELECTROPHORESIS; QUANTITATION; PHARMACEUTICAL ANALYSIS; ALKALOIDS; CODEINE;
D O I
10.1002/mcs.1220050606
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The application of capillary electrophoresis for assaying the drug content of pharmaceutical formulations has been studied. Correction of area for migration times has been found useful in those cases where environmental conditions lead to increased migration time variability. From the results, the feasibility of single-point calibration with an external standard was shown and experimentally verified.
引用
收藏
页码:525 / 530
页数:6
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