学术探索
学术期刊
新闻热点
数据分析
智能评审

Meiotic recombination hotspots

被引：298
作者：
Lichten, M
Goldman, ASH
机构：
[1] Laboratory of Biochemistry, Division of Cancer Biology, National Cancer Institute, Bethesda
来源：
ANNUAL REVIEW OF GENETICS | 1995年 / 29卷
关键词：
crossing-over; gene conversion; meiosis; chromosome structure; chiasmata;
D O I：
10.1146/annurev.ge.29.120195.002231
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Meiotic recombination occurs more frequently in some regions of the eukaryotic genome than in others, with variations of several orders of magnitude observed in frequencies of meiotic exchange per unit physical distance. This article reviews what is known about meiotic recombination hotspots loci, or regions that display a greater than average frequency of meiotic exchange. Hotspots have been most intensively studied in Saccharomyces cerevisiae, which is a major focus of this article. Also reviewed is the current state of knowledge regarding hotspots in other fungi, in maize, in nematodes, in mice, and in humans.
引用
收藏
页码：423 / 444
页数：22
相关论文
共 155 条
  • [1] ALANI E, 1994, GENETICS, V137, P19
  • [2] MOLECULAR CHARACTERIZATION OF A PERICENTRIC-INVERSION IN MOUSE CHROMOSOME-8 IMPLICATES TELOMERES AS PROMOTERS OF MEIOTIC RECOMBINATION
    ASHLEY, T
    CACHEIRO, NLA
    RUSSELL, LB
    WARD, DC
    [J]. CHROMOSOMA, 1993, 102 (02) : 112 - 120
  • [3] SYNCHRONIZED MEIOSIS AND RECOMBINATION IN FISSION YEAST - OBSERVATIONS WITH PAT1-114 DIPLOID-CELLS
    BAHLER, J
    SCHUCHERT, P
    GRIMM, C
    KOHLI, J
    [J]. CURRENT GENETICS, 1991, 19 (06) : 445 - 451
  • [4] GENETIC-CONTROL OF MEIOSIS
    BAKER, BS
    CARPENTER, ATC
    ESPOSITO, MS
    ESPOSITO, RE
    SANDLER, L
    [J]. ANNUAL REVIEW OF GENETICS, 1976, 10 : 53 - 134
  • [5] THE NUCLEOTIDE-SEQUENCE OF THE YEAST ARG4 GENE
    BEACHAM, IR
    SCHWEITZER, BW
    WARRICK, HM
    CARBON, J
    [J]. GENE, 1984, 29 (03) : 271 - 279
  • [6] BENGER JC, 1989, AM J HUM GENET, V45, P606
  • [7] LOCALIZATION AND GENETIC-LINKAGE OF THE HUMAN-IMMUNOGLOBULIN HEAVY-CHAIN GENES AND THE CREATINE-KINASE BRAIN (CKB) GENE - IDENTIFICATION OF A HOT-SPOT FOR RECOMBINATION
    BENGER, JC
    TESHIMA, I
    WALTER, MA
    BRUBACHER, MG
    DAOUK, GH
    COX, DW
    [J]. GENOMICS, 1991, 9 (04) : 614 - 622
  • [8] THE ADE6-GENE OF THE FISSION YEAST SCHIZOSACCHAROMYCES-POMBE HAS THE SAME CHROMATIN STRUCTURE IN THE CHROMOSOME AND IN PLASMIDS
    BERNARDI, F
    KOLLER, T
    THOMA, F
    [J]. YEAST, 1991, 7 (06) : 547 - 558
  • [9] BORTS RH, 1990, GENETICS, V124, P573
  • [10] BRENNER S, 1974, GENETICS, V77, P71
12345678910