ADRENOCORTICAL INSUFFICIENCY WITH NORMAL SERUM CORTISOL-LEVELS AND HYPORENINEMIA IN A PATIENT WITH ACQUIRED-IMMUNODEFICIENCY-SYNDROME (AIDS)

被引：7

作者：

COBBS, R

PEPPER, GM

TORRES, JG

GRUENSPAN, HL

机构：

[1] NEW YORK MED COLL,LINCOLN MED & MENTAL HLTH CTR,DEPT INTERNAL MED,DIV ENDOCRINOL,ROOM 8-28,BRONX,NY 10451

[2] LONG ISL JEWISH MED CTR,DEPT MED,NEW HYDE PK,NY

[3] NEW YORK MED COLL,LINCOLN MED & MENTAL HLTH CTR,DEPT MED,BRONX,NY 10451

来源：

JOURNAL OF INTERNAL MEDICINE | 1991年 / 230卷 / 02期

关键词：

ADRENOCORTICAL FUNCTION; AIDS; CORTISOL; HYPOALDOSTERONISM; HYPORENINEMIA;

D O I：

10.1111/j.1365-2796.1991.tb00427.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The acquired immunodeficiency syndrome (AIDS) has been associated with abnormalities of adrenocortical function [1-4], and hypoaldosteronism due to hyporeninaemic hypoaldosteronism (HHA) [15]. We here report the case of a woman with AIDS associated with orthostatic hypotension, persistent hyponatraemia and hyperkalaemia, in whom basal serum cortisol levels were normal and serum renin activity was low. Subsequent post-mortem examination revealed almost complete adrenocortical destruction. A possible explanation of this apparently contradictory combination of findings is discussed, together with the therapeutic implications for similar cases.

引用

页码：179 / 181

页数：3