STUDIES OF THE BINDING MECHANISM OF CONGO RED TO POLY(L-LYSINE) BY ABSORPTION AND CIRCULAR-DICHROISM SPECTROSCOPY

被引：15

作者：

PIGORSCH, E ^{[1
]}

ELHADDAOUI, A ^{[1
]}

TURRELL, S ^{[1
]}

机构：

[1] UNIV IBN TOFAIL,FAC SCI,DEPT BIOL,UNITE PHARMACOL & TOXICOL,KENITRA,MOROCCO

来源：

JOURNAL OF MOLECULAR STRUCTURE | 1995年 / 348卷

关键词：

D O I：

10.1016/0022-2860(95)08589-N

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The azo dye Congo red (CR) was found to bind to poly(L-lysine) PLL in neutral solution by electrostatic interactions when the side chain amino groups are in the charged state. In basic aqueous solutions the binding of CR was found to result in a conformational transition of uncharged PLL, from the alpha-helix to the beta-sheet structure. The structural change arises from hydrophobic interactions between the dye and the polymer.

引用

页码：61 / 64

页数：4

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