DESIGN OF NONPEPTIDAL LIGANDS FOR A PEPTIDE RECEPTOR - CHOLECYSTOKININ ANTAGONISTS

被引：82

作者：

EVANS, BE ^{[1
]}

RITTLE, KE ^{[1
]}

BOCK, MG ^{[1
]}

DIPARDO, RM ^{[1
]}

FREIDINGER, RM ^{[1
]}

WHITTER, WL ^{[1
]}

GOULD, NP ^{[1
]}

LUNDELL, GF ^{[1
]}

HOMNICK, CF ^{[1
]}

VEBER, DF ^{[1
]}

ANDERSON, PS ^{[1
]}

CHANG, RSL ^{[1
]}

LOTTI, VJ ^{[1
]}

CERINO, DJ ^{[1
]}

CHEN, TB ^{[1
]}

KING, PJ ^{[1
]}

KUNKEL, KA ^{[1
]}

SPRINGER, JP ^{[1
]}

HIRSHFIELD, J ^{[1
]}

机构：

[1] MERCK SHARP & DOHME RES LABS,RAHWAY,NJ 07065

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 07期

关键词：

D O I：

10.1021/jm00390a019

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1229 / 1239

页数：11

共 50 条

[41] METALATION OF DIAZEPAM AND USE OF THE RESULTING CARBANION INTERMEDIATE IN A NEW SYNTHESIS OF 3-SUBSTITUTED DIAZEPAM DERIVATIVES [J].

REITTER, BE ;

SACHDEVA, YP ;

WOLFE, JF .

JOURNAL OF ORGANIC CHEMISTRY, 1981, 46 (20) :3945-3949

[42] NEW PROCEDURE FOR OXIDATION OF 3-SUBSTITUTED INDOLES TO OXINDOLES - MODIFICATION OF TRYPTOPHAN RESIDUES IN PEPTIDES AND PROTEINS [J].

SAVIGE, WE ;

FONTANA, A .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1976, (15) :599-600

[43]

SCHEIBYE S, 1978, B SOC CHIM BELG, V87, P229

[44]

SHIMAMOTO K, 1970, TAKEDA KENKYUSHOHO, V29, P134

[45]

Sternbach L. H., 1968, DRUGS AFFECTING CENT, P237

[46] 1,4-BENZODIAZEPINES - CHEMISTRY AND SOME ASPECTS OF STRUCTURE-ACTIVITY RELATIONSHIP [J].

STERNBACH, LH .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1971, 10 (01) :34-+

[47] QUINAZOLINES AND 1,4-BENZODIAZEPINES .6. HALO-, METHYL-, AND METHYOXY-SUBSTITUTED 1,3-DIHYDRO-5-PHENYL-2H-1,4-BENZODIAZEPIN-2-ONES [J].

STERNBACH, LH ;

FRYER, RI ;

SAUCY, G ;

SACH, G ;

STEMPEL, A ;

METLESICS, W ;

REEDER, E .

JOURNAL OF ORGANIC CHEMISTRY, 1962, 27 (11) :3788-&

[48]

SUNJIC V, 1975, ARZNEIMITTELFORSCH, V25, P340

[49] CHIRAL 1,4-BENZODIAZEPINES .5. SYNTHESIS AND PROPERTIES OF 1,4-BENZODIAZEPIN-2-ONES CONTAINING ALPHA-AMINO-ACIDS AS A PART OF 1,4-DIAZEPINE RING [J].

SUNJIC, V ;

KAJFEZ, F ;

STROMAR, I ;

BLAZEVIC, N ;

KOLBAH, D .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1973, 10 (04) :591-599

[50] DO ANTAGONISTS OF PANCREATIC CHOLECYSTOKININ RECEPTORS INTERACT WITH CENTRAL NERVOUS-SYSTEM CHOLECYSTOKININ RECEPTORS [J].

VIGNA, SR ;

SZECOWKA, J ;

WILLIAMS, JA .

BRAIN RESEARCH, 1985, 343 (02) :394-397

← 1 2 3 4 5 →