INSULIN-MEDIATED REDUCTION OF WHOLE-BODY PROTEIN BREAKDOWN - DOSE-RESPONSE EFFECTS ON LEUCINE METABOLISM IN POST-ABSORPTIVE MEN

被引：348

作者：

FUKAGAWA, NK

MINAKER, KL

ROWE, JW

GOODMAN, MN

MATTHEWS, DE

BIER, DM

YOUNG, VR

机构：

[1] MIT,DEPT APPL BIOL SCI,CAMBRIDGE,MA 02139

[2] MIT,CLIN RES CTR,CAMBRIDGE,MA 02139

[3] BETH ISRAEL HOSP,CHARLES A DANA RES INST,BOSTON,MA 02215

[4] BETH ISRAEL HOSP,HARVARD THORNDIKE LAB,BOSTON,MA 02215

[5] BRIGHAM & WOMENS HOSP,DEPT MED,BOSTON,MA 02115

[6] HARVARD UNIV,DIV AGING,BOSTON,MA 02215

[7] WASHINGTON UNIV,DEPT MED & PEDIAT,ST LOUIS,MO 63110

[8] BOSTON UNIV,SCH MED,DEPT MED & PHYSIOL,BOSTON,MA 02118

[9] BROCKTON N ROXBURY VET ADM MED CTR,CTR GERIATR RES EDUC CLIN,BOSTON,MA 02215

来源：

关键词：

D O I：

10.1172/JCI112240

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：2306 / 2311

页数：6

共 46 条

[11] AMINO-ACID AND PROTEIN-METABOLISM IN DIABETES-MELLITUS
FELIG, P
WAHREN, J
SHERWIN, R
PALAIOLOGOS, G
[J]. ARCHIVES OF INTERNAL MEDICINE, 1977, 137 (04) : 507 - 513
[12] ALANINE . KEY ROLE IN GLUCONEOGENESIS
FELIG, P
POZEFSKY, T
MARLISS, E
CAHILL, GF
[J]. SCIENCE, 1970, 167 (3920) : 1003 - &
[13] FINK RI, 1983, J CLIN INVEST, V71, P1523, DOI 10.1172/JCI110908
[14] INSULIN-DEPENDENT METABOLISM OF BRANCHED-CHAIN AMINO-ACIDS IN OBESITY
FORLANI, G
VANNINI, P
MARCHESINI, G
ZOLI, M
CIAVARELLA, A
PISI, E
[J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 1984, 33 (02): : 147 - 150
[15] FULKS RM, 1975, J BIOL CHEM, V250, P290
[16] GERTNER J, 1984, DIABETES S1, V33, pA2
[17] STIMULATORY ACTION OF INSULIN ON LEUCINE UPTAKE + METABOLISM IN ADIPOSE TISSUE
GOODMAN, HM
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1964, 206 (01): : 129 - &
[18] EFFECTS OF STARVATION, DIABETES AND ACUTE INSULIN-TREATMENT ON THE REGULATION OF POLYPEPTIDE-CHAIN INITIATION IN RAT SKELETAL-MUSCLE
HARMON, CS
PROUD, CG
PAIN, VM
[J]. BIOCHEMICAL JOURNAL, 1984, 223 (03) : 687 - 696
[19] BRANCHED-CHAIN AMINO-ACIDS AS A MAJOR SOURCE OF ALANINE NITROGEN IN MAN
HAYMOND, MW
MILES, JM
[J]. DIABETES, 1982, 31 (01) : 86 - 89
[20] HOFFER LJ, 1982, THESIS MIT CAMBRIDGE