PRACTICAL METHODOLOGY OF METAANALYSES (OVERVIEWS) USING UPDATED INDIVIDUAL PATIENT DATA

被引：347

作者：

STEWART, LA

CLARKE, MJ

机构：

[1] UNIV OXFORD,CLIN TRIAL SERV UNIT,OXFORD OX2 6HE,ENGLAND

[2] RADCLIFFE INFIRM,IMPERIAL CANC RES FUND,CANC STUDIES UNIT,OXFORD OX2 6HE,ENGLAND

来源：

STATISTICS IN MEDICINE | 1995年 / 14卷 / 19期

关键词：

D O I：

10.1002/sim.4780141902

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Meta-analyses using updated individual patient data may provide the most reliable means of combining data from similar randomized controlled trials. The benefits of this approach to systematic reviews are described. Guidance, based on the experience of several groups who have undertaken such projects, is given. This includes practical advice on initiating and maintaining collaboration, the time and resources required to undertake these usually international projects and methods of data checking and validation. Example proforma are included.

引用

页码：2057 / 2079

页数：23