SYNTHESES OF [2-C-14] 2,5'-ANHYDRO-3'-AZIDO-3'-DEOXYTHYMIDINE AND [2-C-14] 2,5'-ANHYDRO-3'-AZIDO-2',3'-DIDEOXY-5-IODOURIDINE - INHIBITORS OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV-1)

被引：1

作者：

LIN, TS ^{[1
]}

LIU, MC ^{[1
]}

AUGUST, EM ^{[1
]}

BIRKS, EM ^{[1
]}

PRUSOFF, WH ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,CTR COMPREHENS CANC,NEW HAVEN,CT 06510

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 1991年 / 29卷 / 12期

关键词：

AZT; 2-C-14] 2,5'-ANHYDRO-3'-AZIDO-3'-DEOXYTHYMIDINE; 2-C-14] 2,5'-ANHYDRO-3'-AZIDO-2',3'-DIDEOXY-5-IODURIDINE; HPLC; MILD REACTION CONDITION;

D O I：

10.1002/jlcr.2580291208

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The syntheses of [2-C-14] 2,5'-anhydro-3'-azido-3'-deoxythymidine and [2-C-14] 2,5'-anhydro-3'-azido-2',3'-dideoxy-5-iodouridine in a one pot operation under mild conditions are described.

引用

页码：1315 / 1321

页数：7

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