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TN924, A CHROMOSOME-BORNE TRANSPOSON ENCODING HIGH-LEVEL GENTAMICIN RESISTANCE IN ENTEROCOCCUS-FAECALIS

被引：17
作者：
THAL, LA
CHOW, JW
CLEWELL, DB
ZERVOS, MJ
机构：
[1] WILLIAM BEAUMONT HOSP,DEPT MED,DIV INFECT DIS,ROYAL OAK,MI 48073
[2] WILLIAM BEAUMONT HOSP,DEPT BIOL & MAT SCI,ROYAL OAK,MI 48072
[3] WILLIAM BEAUMONT HOSP,DEPT MICROBIOL,ROYAL OAK,MI 48072
[4] WILLIAM BEAUMONT HOSP,DEPT IMMUNOL,ROYAL OAK,MI 48072
[5] UNIV MICHIGAN,ANN ARBOR,MI 48109
[6] WAYNE STATE UNIV,DETROIT,MI
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 05期
关键词：
D O I：
10.1128/AAC.38.5.1152
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Enterococcus faecalis SF350 is a clinical isolate from Winnipeg, Canada, with high-level (MIC > 2,000 mu g/ml) gentamicin resistance. The genetic determinant for gentamicin resistance was located on the chromosome of SF350 and could be mobilized by a coresident conjugative plasmid, pYN120. Genetic and physical analyses showed that the gentamicin resistance determinant was located on a 27-kb transposable element which was designated Tn924.
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页码：1152 / 1156
页数：5
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