TN924, A CHROMOSOME-BORNE TRANSPOSON ENCODING HIGH-LEVEL GENTAMICIN RESISTANCE IN ENTEROCOCCUS-FAECALIS

被引：17

作者：

THAL, LA

CHOW, JW

CLEWELL, DB

ZERVOS, MJ

机构：

[1] WILLIAM BEAUMONT HOSP,DEPT MED,DIV INFECT DIS,ROYAL OAK,MI 48073

[2] WILLIAM BEAUMONT HOSP,DEPT BIOL & MAT SCI,ROYAL OAK,MI 48072

[3] WILLIAM BEAUMONT HOSP,DEPT MICROBIOL,ROYAL OAK,MI 48072

[4] WILLIAM BEAUMONT HOSP,DEPT IMMUNOL,ROYAL OAK,MI 48072

[5] UNIV MICHIGAN,ANN ARBOR,MI 48109

[6] WAYNE STATE UNIV,DETROIT,MI

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 05期

关键词：

D O I：

10.1128/AAC.38.5.1152

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Enterococcus faecalis SF350 is a clinical isolate from Winnipeg, Canada, with high-level (MIC > 2,000 mu g/ml) gentamicin resistance. The genetic determinant for gentamicin resistance was located on the chromosome of SF350 and could be mobilized by a coresident conjugative plasmid, pYN120. Genetic and physical analyses showed that the gentamicin resistance determinant was located on a 27-kb transposable element which was designated Tn924.

引用

页码：1152 / 1156

页数：5