ENZYMATIC RESOLUTION IN ORGANIC MEDIA - SYNTHESIS OF OPTICALLY-ACTIVE FURANOLS POSSESSING A FLUOROALKYL GROUP

被引：10

作者：

TAKEDA, M ^{[1
]}

ISHIZUKA, T ^{[1
]}

ITOH, K ^{[1
]}

KITAZUME, T ^{[1
]}

机构：

[1] TOKYO INST TECHNOL, DEPT BIOENGN, MIDORI KU, YOKOHAMA, KANAGAWA 226, JAPAN

来源：

JOURNAL OF FLUORINE CHEMISTRY | 1995年 / 75卷 / 01期

关键词：

ENZYMATIC ESTERIFICATION; LIPASE; CHIRAL FLUOROALKYLATED FURANOL;

D O I：

10.1016/0022-1139(95)03312-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Furanols possessing a fluoroalkyl group were resolved into the corresponding optically active forms via enzymatic esterification in organic media.

引用

页码：111 / 113

页数：3

共 14 条

[1] TRANSITION-STATE ANALOGS AS LIGANDS FOR AFFINITY PURIFICATION OF JUVENILE-HORMONE ESTERASE [J].

ABDELAAL, YAI ;

HAMMOCK, BD .

SCIENCE, 1986, 233 (4768) :1073-1076

[2] FLUORO KETONE CONTAINING PEPTIDES AS INHIBITORS OF HUMAN RENIN [J].

FEARON, K ;

SPALTENSTEIN, A ;

HOPKINS, PB ;

GELB, MH .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (09) :1617-1622

[3] A GENERAL-ROUTE TO N'-(2,2-DIFLUORO-3-HYDROXYALKANOYL)NORNICOTINES [J].

FUKUDA, H ;

KITAZUME, T .

JOURNAL OF FLUORINE CHEMISTRY, 1995, 74 (02) :171-176

[4]

IMPERIALI B, 1987, BIOCHEMISTRY-US, V26, P2682

[5]

Itoh K., 1993, Ferroelectrics, V148, P85, DOI 10.1080/00150199308019934

[6]

ITOH K, IN PRESS J MATER SCI

[7] NOVEL STEREOSELECTIVE SYNTHESES OF CHIRAL 2,6-DIDEOXY-6,6,6-TRIFLUORO SUGARS VIA ENZYMATIC RESOLUTION OF TRIFLUOROMETHYLATED PROPYNYLIC ALCOHOL [J].

MIZUTANI, K ;

YAMAZAKI, T ;

KITAZUME, T .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (01) :51-52

[8] BIOCHEMICAL REDUCTION OF 3-OXOALKANOIC ESTERS BY A BOTTOM-FERMENTATION YEAST, SACCHAROMYCES-CEREVISIAE IFO-0565 [J].

MOCHIZUKI, N ;

SUGAI, T ;

OHTA, H .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1994, 58 (09) :1666-1670

[9]

Suzuki Y., 1993, Ferroelectrics, V147, P109, DOI 10.1080/00150199308217186

[10] ENANTIOSELECTIVE SYNTHESIS OF BETA,BETA-DIFLUOROMALIC ACID VIA ENZYMATIC RESOLUTION OF FURYL SUBSTITUTED DERIVATIVE [J].

TSUKAMOTO, T ;

YOSHIYAMA, T ;

KITAZUME, T .

TETRAHEDRON-ASYMMETRY, 1991, 2 (08) :759-762

← 1 2 →