DOES LYMPHANGIOGRAPHY HAVE ANY ROLE IN THE MANAGEMENT OF EARLY NONSEMINOTAMOUS GERM-CELL TUMORS

被引:8
作者
HARDING, M
DALL, B
CORBETT, R
VALLANCE, R
KAYE, SB
机构
[1] UNIV GLASGOW,CRC DEPT MED ONCOL,GLASGOW G12 8QQ,SCOTLAND
[2] WESTERN INFIRM & ASSOCIATED HOSP,DEPT RADIOL,GLASGOW G11 6NT,SCOTLAND
[3] GARTNAVEL ROYAL HOSP,GLASGOW G12 0YN,SCOTLAND
[4] HAIRMYRES HOSP,E KILBRIDE,LANARK,SCOTLAND
关键词
D O I
10.1016/S0009-9260(05)80598-7
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Since 1980, 51 patients with non-seminomatous testicular germ cell tumours (NSGCT) and normal or equivocal initial computed tomography (CT) imaging have also had lymphography performed. Radiological records of these patients were reviewed to determine the extent to which lymphography (LAG) contributed to patient management. Forty-nine patients were retrospectively confirmed to have normal CT but of these 14 (29%) were considered to have nodal metastatic disease on lymphography. These patients and seven others with marker only evidence of tumour received chemotherapy and all remain disease-free. Six of thirty-six patients relapsed, but the incidence was not significantly higher in patients who did not undergo LAG (2 of 8: 25%) than among those whose initial LAG was normal (4 of 28: 14%). All relapsing tumours achieved a complete remission with chemotherapy. We conclude that although LAG may have resulted in earlier treatment for some patients, several may have been overtreated on the basis of radiological abnormalities which did not represent metastatic disease. We believe that the success of salvage chemotherapy means that LAG may be safely abandoned as a staging procedure for NSGCT. © 1990 The Royal College of Radiologists, 38 Portland Place, London W1N 3DG, UK. All rights reserved.
引用
收藏
页码:392 / 394
页数:3
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