ASSESSMENT OF AN INSITU RAT INTESTINE PREPARATION WITH PERFUSED VASCULAR BED FOR STUDYING THE ABSORPTION AND 1ST-PASS METABOLISM OF DRUGS

被引：12

作者：

CASTLE, SJ

TUCKER, GT

WOODS, HF

UNDERWOOD, JCE

NICHOLSON, CM

HAVLER, ME

LEWIS, CJ

FLOCKHART, IR

LLOYDJONES, G

机构：

[1] UNIV SHEFFIELD,ROYAL HALLAMSHIRE HOSP,DEPT THERAPEUT,SHEFFIELD S10 2JF,S YORKSHIRE,ENGLAND

[2] UNIV SHEFFIELD,SCH MED,DEPT PATHOL,SHEFFIELD S10 2JF,S YORKSHIRE,ENGLAND

[3] RECKITT & COLMAN LTD,DIV PHARMACEUT,HULL HU8 7DS,N HUMBERSIDE,ENGLAND

来源：

JOURNAL OF PHARMACOLOGICAL METHODS | 1985年 / 14卷 / 04期

关键词：

D O I：

10.1016/0160-5402(85)90002-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：255 / 274

页数：20

相关论文

共 18 条

[11] HISTOLOGICAL REEVALUATION OF EVERTED GUT TECHNIQUE FOR STUDYING INTESTINAL ABSORPTION
LEVINE, RR
MCNARY, WF
KORNGUTH, PJ
LEBLANC, R
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1970, 9 (02) : 211 - &
[12] LLOYD B, 1978, CLIN CHEM, V24, P1724
[13] TRANSPORT AND METABOLISM OF GLUCOSE BY RAT SMALL-INTESTINE
NICHOLLS, TJ
LEESE, HJ
BRONK, JR
[J]. BIOCHEMICAL JOURNAL, 1983, 212 (01) : 183 - 187
[14] RELEVANCE OF BLOOD-FLOW FOR THE ABSORPTION OF DRUGS IN THE VASCULARLY PERFUSED, ISOLATED INTESTINE OF THE RAT
OCHSENFAHRT, H
[J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1979, 306 (02) : 105 - 112
[15] METABOLISM OF PHENOLIC OPIATES BY RAT INTESTINE
RANCE, MJ
SHILLINGFORD, JS
[J]. XENOBIOTICA, 1977, 7 (09) : 529 - 536
[16] VASCULARLY PERFUSED RAT SMALL-INTESTINE - A RESEARCH MODEL FOR DRUG ABSORPTION
SAKAI, K
AKIMA, M
HINOHARA, Y
SASAKI, M
NIKI, R
[J]. JAPANESE JOURNAL OF PHARMACOLOGY, 1980, 30 (02) : 231 - 241
[17] THE USE OF SACS OF EVERTED SMALL INTESTINE FOR THE STUDY OF THE TRANSFERENCE OF SUBSTANCES FROM THE MUCOSAL TO THE SEROSAL SURFACE
WILSON, TH
WISEMAN, G
[J]. JOURNAL OF PHYSIOLOGY-LONDON, 1954, 123 (01): : 116 - 125
[18] VASCULAR PERFUSION OF ISOLATED RAT GUT . NOREPINEPHRINE AND GLUCOCORTICOID REQUIREMENT
WINDMUELLER, HG
SPAETH, AE
GANOTE, CE
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1970, 218 (01): : 197 - +