CEPHALOSPORIN-C BIOSYNTHESIS - STEREOCHEMISTRY OF THE INCORPORATION OF D,L,D-ALPHA-AMINODIPOYL-CYSTEINYL-(3S)-[2-2H,4-C-13]VALINE INTO BETA-LACTAM COMPOUNDS

被引：12

作者：

BALDWIN, JE ^{[1
]}

ADLINGTON, RM ^{[1
]}

CROUCH, NP ^{[1
]}

TURNER, NJ ^{[1
]}

SCHOFIELD, CJ ^{[1
]}

机构：

[1] UNIV OXFORD,DYSON PERRINS LAB,OXFORD OX1 3QY,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1989年 / 16期

关键词：

D O I：

10.1039/c39890001141

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：1141 / 1143

页数：3

共 13 条

[1] STUDIES ON BIOSYNTHESIS OF BETA-LACTAM ANTIBIOTICS .1. STEREOSPECIFIC SYNTHESES OF (2RS,3S)-[4,4,4-H-2(3)]-VALINE, (2RS,3S)-[4-H-3]-VALINE, (2RS,3R)-[4-H-3]-VALINE, AND (2RS,3S)-[4-C-13]-VALINE - INCORPORATION OF (2RS,3S)-[4-C-13]-VALINE INTO PENICILLIN-V
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[2] PENICILLIN BIOSYNTHESIS - ACTIVE-SITE MAPPING WITH AMINOADIPOYLCYSTEINYLVALINE VARIANTS
BALDWIN, JE
ABRAHAM, EP
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BAHADUR, GA
CHAKRAVARTI, B
DOMAYNEHAYMAN, BP
FIELD, LD
FLITSCH, SL
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[3] STEPWISE HYDROGEN REMOVAL IN THE ENZYMATIC RING EXPANSION OF PENICILLIN-N TO DEACETOXYCEPHALOSPORIN-C
BALDWIN, JE
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[4] PURIFICATION AND INITIAL CHARACTERIZATION OF AN ENZYME WITH DEACETOXYCEPHALOSPORIN-C SYNTHETASE AND HYDROXYLASE-ACTIVITIES
BALDWIN, JE
ADLINGTON, RM
COATES, JB
CRABBE, MJC
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[J]. BIOCHEMICAL JOURNAL, 1987, 245 (03) : 831 - 841
[5] STEREOSPECIFICITY OF CARBON-SULFUR BOND FORMATION IN PENICILLIN BIOSYNTHESIS
BALDWIN, JE
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TING, HH
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[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (02) : 110 - 113
[6] CEPHALOSPORIN-C BIOSYNTHESIS - A BRANCHED PATHWAY SENSITIVE TO A KINETIC ISOTOPE EFFECT
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[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (21) : 1651 - 1654
[7] SUBSTRATE-SPECIFICITY OF CLONED DEACETOXYCEPHALOSPORIN-C DEACETYLCEPHALOSPORIN C SYNTHETASE
BALDWIN, JE
ADLINGTON, RM
CROUCH, NP
COATES, JB
KEEPING, JW
SCHOFIELD, CJ
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SUTHERLAND, JD
[J]. JOURNAL OF ANTIBIOTICS, 1988, 41 (11) : 1694 - 1695
[8] BALDWIN JE, 1988, NAT PROD REP, P129
[9] BALDWIN JE, 1973, J AM CHEM SOC, V95, P3797
[10] SYNTHESIS AND INCORPORATION OF (2S,3S)-[4-C-13]VALINE INTO BETA-LACTAM ANTIBIOTICS
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BRADLEY, CH
SIH, CJ
FAWCETT, P
ABRAHAM, EP
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (18) : 6149 - 6150

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