NMR ANALYSIS OF THE ADDITION OF NH, OH AND P-V-H FUNCTIONAL MOLECULES TO DIETHYL ETHENYLIDENE-BISPHOSPHONATE - SYNTHESIS OF FUNCTIONALIZED GEM-BISPHOSPHONATES

被引：15

作者：

BAILLY, T

BURGADA, R

机构：

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1994年 / 86卷 / 1-4期

关键词：

BIS PHOSPHONATES; SPIROPHOSPHORANES; ETHENYLIDENE GEM BIS PHOSPHONATE; MICHAEL ADDITION; PHOSPHORANE-BIS PHOSPHONATES; DIASTEREOTOPIE AND STEREOMUTATIONS;

D O I：

10.1080/10426509408018407

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Tetraethyl ethenylidene bis phosphonate can undergo facile Michael type addition reaction with amines, alcohols, water, aminoacid and spirophosphoranes bearing a P-H bond. The stability of these compounds was investigated and the reversibility of the reaction was demonstrated in the case of methylamine.

引用

页码：217 / 228

页数：12

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[21]

STURTZ G, 1991, SYNTHESIS-STUTTGART, V8, P661

[22] ALPHA-KETOPHOSPHONATES AND CYCLIC ESTERS OF HYDROXYMETHYLENE DIPHOSPHONATES - SYNTHESIS, STRUCTURE AND HYDROLYSIS [J].