DEVELOPMENT OF RESISTANCE TO CHLOROQUINE BY PLASMODIUM-VIVAX IN MYANMAR

被引：98

作者：

MARLARTHAN

MYATPHONEKYAW

AYEYUSOE

KHAINGKHAINGGYI

MASABAI

MYINTOO

机构：

[1] MINIST HLTH,DEPT MED RES,DIV PARASITOL RES,RANGOON 11191,MYANMAR

[2] DEF SERV GEN HOSP,CLIN MALARIA RES UNIT,MINGALADON,MYANMAR

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1995年 / 89卷 / 03期

关键词：

MALARIA; PLASMODIUM VIVAX; CHLOROQUINE RESISTANCE; MYANMAR;

D O I：

10.1016/0035-9203(95)90556-1

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Fifty patients with Plasmodium vivax infection were treated with the standard regimen of chloroquine phosphate (1500 mg over 3 d) followed by primaquine (45 mg immediately and then weekly for 8 weeks); 43 patients had sensitive infections but recrudescences of parasitaemia occurred between days 3 and 14 with RI, RII and RIII patterns in one, 3 and 3 patients, respectively. All the chloroquine-resistant cases were again treated with chloroquine (1500 mg) and no further recrudescence or relapse was detected on days 21 and 28. This study indicates that chloroquine is losing its efficacy against P. vivax in Myanmar.

引用

页码：307 / 308

页数：2

共 11 条

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