HEAT-SHOCK PROTEIN-PEPTIDE COMPLEXES IN CANCER-IMMUNOTHERAPY

被引:120
作者
SRIVASTAVA, PK [1 ]
UDONO, H [1 ]
机构
[1] OKAYAMA UNIV, SCH MED, DEPT PARASITOL & IMMUNOL, OKAYAMA 700, JAPAN
关键词
D O I
10.1016/0952-7915(94)90076-0
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Heat shock proteins (HSPs) are associated with a broad spectrum of peptides derived from the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits protective immunity against tumors or other cells used as the source of HSPs. These observations suggest that HSP-peptide complexes are suitable as vaccines against cancers and infectious diseases.
引用
收藏
页码:728 / 732
页数:5
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