HEAT-SHOCK PROTEIN-PEPTIDE COMPLEXES IN CANCER-IMMUNOTHERAPY

被引：120

作者：

SRIVASTAVA, PK ^{[1
]}

UDONO, H ^{[1
]}

机构：

[1] OKAYAMA UNIV, SCH MED, DEPT PARASITOL & IMMUNOL, OKAYAMA 700, JAPAN

来源：

CURRENT OPINION IN IMMUNOLOGY | 1994年 / 6卷 / 05期

关键词：

D O I：

10.1016/0952-7915(94)90076-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Heat shock proteins (HSPs) are associated with a broad spectrum of peptides derived from the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits protective immunity against tumors or other cells used as the source of HSPs. These observations suggest that HSP-peptide complexes are suitable as vaccines against cancers and infectious diseases.

引用

页码：728 / 732

页数：5

共 30 条

[11] HEAT-SHOCK PROTEIN HSP60-REACTIVE GAMMA-DELTA-CELLS - A LARGE, DIVERSIFIED LYMPHOCYTE-T SUBSET WITH HIGHLY FOCUSED SPECIFICITY [J].

OBRIEN, RL ;

FU, YX ;

CRANFILL, R ;

DALLAS, A ;

ELLIS, C ;

REARDON, C ;

LANG, J ;

CARDING, SR ;

KUBO, R ;

BORN, W .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (10) :4348-4352

[12]

OLD LJ, 1981, CANCER RES, V41, P361

[13]

PALLADINO MA, 1987, CANCER RES, V47, P5074

[14] TUMOR-ANTIGENS - A NEW LOOK FOR THE 1990S [J].

PARDOLL, DM .

NATURE, 1994, 369 (6479) :357-358

[15] PHAGOCYTIC PROCESSING OF BACTERIAL-ANTIGENS FOR CLASS-I MHC PRESENTATION TO T-CELLS [J].

PFEIFER, JD ;

WICK, MJ ;

ROBERTS, RL ;

FINDLAY, K ;

NORMARK, SJ ;

HARDING, CV .

NATURE, 1993, 361 (6410) :359-362

[16]

ROHRER JW, 1994, J IMMUNOL, V152, P754

[17]

SCIAMMAS R, 1994, J IMMUNOL, V152, P5392

[18] THE SEROLOGICALLY UNIQUE CELL-SURFACE ANTIGEN OF ZAJDELA ASCITIC HEPATOMA IS ALSO ITS TUMOR-ASSOCIATED TRANSPLANTATION ANTIGEN [J].

SRIVASTAVA, PK ;

DAS, MR .

INTERNATIONAL JOURNAL OF CANCER, 1984, 33 (03) :417-422

[19] TUMOR REJECTION ANTIGENS OF CHEMICALLY-INDUCED SARCOMAS OF INBRED MICE [J].

SRIVASTAVA, PK ;

DELEO, AB ;

OLD, LJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (10) :3407-3411

[20] PEPTIDE-BINDING HEAT-SHOCK PROTEINS IN THE ENDOPLASMIC-RETICULUM - ROLE IN IMMUNE-RESPONSE TO CANCER AND IN ANTIGEN PRESENTATION [J].

SRIVASTAVA, PK .

ADVANCES IN CANCER RESEARCH, VOL 62, 1993, 62 :153-177

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