SYNTHESIS OF NUCLEOTIDE LIPOPHILIC PRODRUGS CONTAINING 2 INHIBITORS TARGETED AGAINST DIFFERENT PHASES OF THE HIV REPLICATION CYCLE

被引：11

作者：

BONNAFFE, D ^{[1
]}

DUPRAZ, B ^{[1
]}

UGHETTOMONFRIN, J ^{[1
]}

NAMANE, A ^{[1
]}

DINH, TH ^{[1
]}

机构：

[1] INST PASTEUR,UNITE CHIM ORGAN,CNRS,URA 487,F-75724 PARIS 15,FRANCE

来源：

NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期

关键词：

D O I：

10.1080/15257779508012471

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We describe the preparation of nucleoside acyl 5'-di or 5'-triphosphates, containing a nucleoside analog moiety and 13-oxa-myristic acid as lipophilic chain. At physiological pH these products liberated exclusively the corresponding nucleotides.

引用

页码：783 / 787

页数：5

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