Risk Factors Related to Low Ankle-Brachial Index Measured by Traditional and Modified Definition in Hypertensive Elderly Patients

被引:7
作者
Monteiro, Raphael [1 ]
Marto, Renata [1 ]
Neves, Andmario Fritsch [1 ]
机构
[1] State Univ Rio Janeiro, Dept Clin Med, Avenida 28 Setembro 77,Sala 329, BR-20551030 Rio De Janeiro, RJ, Brazil
关键词
D O I
10.1155/2012/163807
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Peripheral arterial disease (PAD) increases with age and ankle-brachial index (ABI) <= 0.9 is a noninvasive marker of PAD. The purpose of this study was to identify risk factors related to a low ABI in the elderly using two different methods of ABI calculation (traditional and modified definition using lower instead of higher ankle pressure). A cross-sectional study was carried out with 65 hypertensive patients aged 65 years or older. PAD was present in 18% of individuals by current ABI definition and in 32% by modified method. Diabetes, cardiovascular diseases, metabolic syndrome, higher levels of systolic blood pressure and pulse pressure, elevated risk by Framingham Risk Score (FRS), and a higher number of total and antihypertensive drugs in use were associated with low ABI by both definitions. Smoking and LDL-cholesterol were associated with low ABI only by the modified definition. Low ABI by the modified definition detected 9 new cases of PAD but cardiovascular risk had not been considered high in 3 patients when calculated by FRS. In conclusion, given that a simple modification of ABI calculation would be able to identify more patients at high risk, it should be considered for cardiovascular risk prediction in all elderly hypertensive outpatients.
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页数:7
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共 40 条
[11]  
Franklin SS, 1997, CIRCULATION, V96, P308
[12]   Prevalence of lower-extremity disease in the US adult population ≥40 years of age with and without diabetes -: 1999-2000 National Health and Nutrition Examination Survey [J].
Gregg, EW ;
Sorlie, P ;
Paulose-Ram, R ;
Gu, QP ;
Eberhardt, MS ;
Wolz, M ;
Burt, V ;
Curtin, L ;
Engelgau, M ;
Geiss, L .
DIABETES CARE, 2004, 27 (07) :1591-1597
[13]  
Hirsch AT, 2006, CIRCULATION, V113, pE463, DOI 10.1161/CIRCULATIONAHA.106.174526
[14]   Association of Chronic Kidney Disease With the Spectrum of Ankle Brachial Index The CHS (Cardiovascular Health Study) [J].
Ix, Joachim H. ;
Katz, Ronit ;
De Boer, Ian H. ;
Kestenbaum, Brian R. ;
Allison, Matthew A. ;
Siscovick, David S. ;
Newman, Anne B. ;
Sarnak, Mark J. ;
Shlipak, Michael G. ;
Criqui, Michael H. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (13) :1176-1184
[15]   STUDIES OF ILLNESS IN THE AGED - THE INDEX OF ADL - A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION [J].
KATZ, S ;
FORD, AB ;
MOSKOWITZ, RW ;
JACKSON, BA ;
JAFFE, MW .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1963, 185 (12) :914-919
[16]   Measurement, calculation, and normal range of the ankle-arm index: A bibliometric analysis and recommendation for standardization [J].
Klein, S ;
Hage, JJ .
ANNALS OF VASCULAR SURGERY, 2006, 20 (02) :282-292
[17]   LACK OF ASSOCIATION BETWEEN CHOLESTEROL AND CORONARY HEART-DISEASE MORTALITY AND MORBIDITY AND ALL-CAUSE MORTALITY IN PERSONS OLDER THAN 70 YEARS [J].
KRUMHOLZ, HM ;
SEEMAN, TE ;
MERRILL, SS ;
DELEON, CFM ;
VACCARINO, V ;
SILVERMAN, DI ;
TSUKAHARA, R ;
OSTFELD, AM ;
BERKMAN, LF .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 272 (17) :1335-1340
[18]   Serum uric acid in hypertensive patients with and without peripheral arterial disease [J].
Langlois, M ;
De Bacquer, D ;
Duprez, D ;
De Buyzere, M ;
Delanghe, J ;
Blaton, V .
ATHEROSCLEROSIS, 2003, 168 (01) :163-168
[19]   Ankle-to-brachial index and dementia - The Honolulu-Asia aging study [J].
Laurin, Danielle ;
Masaki, Kamal H. ;
White, Lon R. ;
Launer, Lenore J. .
CIRCULATION, 2007, 116 (20) :2269-2274
[20]   Correlation between brachial-ankle pulse wave velocity and arterial compliance and cardiovascular risk factors in elderly patients with arteriosclerosis [J].
Li, Baoying ;
Gao, Haiqing ;
Li, Xiaoli ;
Liu, Yuanping ;
Wang, Min .
HYPERTENSION RESEARCH, 2006, 29 (05) :309-314