NOVEL SYNTHESIS OF THE ALDOSE REDUCTASE INHIBITOR SORBINIL VIA AMIDOALKYLATION, INTRAMOLECULAR OXAZOLIDIN-5-ONE ALKYLATION, AND CHYMOTRYPSIN RESOLUTION

被引：30

作者：

DIRLAM, NL ^{[1
]}

MOORE, BS ^{[1
]}

URBAN, FJ ^{[1
]}

机构：

[1] PFIZER CENT RES, GROTON, CT 06340 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1987年 / 52卷 / 16期

关键词：

D O I：

10.1021/jo00392a017

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：3587 / 3591

页数：5

共 30 条

[1] RESOLUTION OF ALPHA-METHYL AMINO ESTERS BY CHYMOTRYPSIN [J].

ANANTHARAMAIAH, GM ;

ROESKE, RW .

TETRAHEDRON LETTERS, 1982, 23 (33) :3335-3336

[2] HERSTELLUNG VON ALPHA-AMINOSAUREESTERN DURCH ALKOHOLYSE DER METHYLESTER [J].

BRENNER, M ;

HUBER, W .

HELVETICA CHIMICA ACTA, 1953, 36 (05) :1109-1115

[3] STEREOSPECIFICITY IN HYDROLYSIS BY ALPHA-CHYMOTRYPSIN OF ESTERS OF ALPHA,ALPHA DISUBSTITUTED ACETIC AND BETA,BETA-DISUBSTITUTED PROPIONIC ACIDS [J].

COHEN, SG ;

SCHULTZ, RM ;

WEINSTEIN, SY .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1966, 88 (22) :5315-+

[4]

Cue B.W., 1984, Patent No. [US 4435578 A, 4435578]

[5] 1,3-DIPOLAR CYCLOADDITION REACTIONS .53. QUESTION OF 1,3-DIPOLAR NATURE OF DELTA2-OXAZOLIN-5-ONES [J].

GOTTHARDT, H ;

HUISGEN, R ;

BAYER, HO .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (14) :4340-+

[6] STERICALLY CONTROLLED SYNTHESES OF OPTICALLY-ACTIVE ORGANIC COMPOUNDS .18. ASYMMETRIC SYNTHESES OF AMINO-ACIDS BY ADDITION OF HYDROGEN-CYANIDE TO SCHIFF-BASES [J].

HARADA, K ;

OKAWARA, T .

JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (04) :707-710

[7] AZLACTONE SYNTHESIS - 2-PHENYL-2-OXAZOLIN-5-ONE [J].

HOYNG, CF ;

MCKENNA, M ;

NOVAK, K .

SYNTHETIC COMMUNICATIONS, 1980, 10 (10) :761-766

[8]

JONES JB, 1977, TECHNIQUES CHEM, V10, pCH4

[9] SYNTHESIS AND ABSOLUTE-CONFIGURATION OF 2-ALKYL-CHROMAN-4-SPIRO-HYDANTOIN DERIVATIVES [J].

KAWAKAMI, Y ;

NAGAI, Y ;

ONO, H ;

UEDA, K ;

SATO, T ;

TANAKA, S .

HETEROCYCLES, 1984, 21 :583-583

[10] REACTIONS OF OXAZOLIN-5-ONE ANIONS .8. ALPHA-SUBSTITUTED ALPHA-AMINO-ACIDS VIA ALKYLATION OF OXAZOLIN-5-ONES [J].

KUBEL, B ;

GRUBER, P ;

HURNAUS, R ;

STEGLICH, W .

CHEMISCHE BERICHTE-RECUEIL, 1979, 112 (01) :128-137

← 1 2 3 →