SKIN-RESPONSE TO TUBERCULIN IN PIG FETUSES AND GERM-FREE PIGLETS

被引：4

作者：

TREBICHAVSKY, I

KOVARU, F

REHAKOVA, Z

MANDEL, L

POSPISIL, R

机构：

[1] Department of Immunology and Gnotobiology, Institute of Microbiology, Czechoslovak Academy of Sciences, Prague

来源：

IMMUNOLOGY LETTERS | 1992年 / 33卷 / 03期

关键词：

PPD; SKIN; T-CELL; FETUS; GERM-FREE PIG;

D O I：

10.1016/0165-2478(92)90072-V

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cellular response to intradermally administered PPD (2 TU) was demonstrated in pig foetuses of various ages and in germ-free piglets. CD2 +, CD4 +, CD8 -, 86D -, SLA - D - T lymphocytes were the predominant cells in the skin tuberculin reaction in both foetuses and germ-free animals. Reactive T cells were observed as early as in mid-gestation, whereas SLA-D+ (porcine MHC class II) cells appeared only in older foetuses. Polymorphonuclear leukocytes were never observed in the PPD reaction.

引用

页码：271 / 276

页数：6

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