PITUITARY-ADENOMA PROLIFERATIVE INDEXES AND RISK OF RECURRENCE

被引：20

作者：

CARBONI, P ^{[1
]}

DETTA, A ^{[1
]}

HITCHCOCK, ER ^{[1
]}

POSTANS, R ^{[1
]}

机构：

[1] MIDLAND CTR NEUROSURG & NEUROL,DEPT NEUROSURG,MOLEC NEURO ONCOL LAB,SMETHWICK B67 7JK,W MIDLANDS,ENGLAND

来源：

BRITISH JOURNAL OF NEUROSURGERY | 1992年 / 6卷 / 01期

关键词：

PROLIFERATIVE INDEX; BROMODEOXYURIDINE; PITUITARY NEOPLASM; IMMUNOCYTOCHEMISTRY; CELL KINETICS; PITUITARY HORMONES;

D O I：

10.3109/02688699209002899

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Twenty unselected pituitary adenomas have been examined for proliferative indices (PIs), and anterior pituitary hormone expression. All but two of the tumours were non-functional with proliferative indices from less than 0.1 to 0.5%. Two tumours were null cell adenomas with PIs < 0.1 and 0.2%. The PIs of the three recurrent tumours was less than 1.0%. Gonadotrophin and TSH immunoreactivity was heterogenous and was found in 12/20 (60%) of the tumours. There was no significant relationship between PI, hormone expression or any other measured parameter. The biological behaviour of pituitary adenomas with a PI of less than 0.1% is uncertain, but those with a PI of greater than 0.1% are more likely to recur although longer follow-up is needed to confirm this.

引用

页码：33 / 40

页数：8