CHEMOSELECTIVITY AND ENHANCED ACTIVITY OF POLY(ETHYLENE GLYCOL)-MODIFIED LIPASES ACYLATING HYDROPHILIC AMINO-ACID DERIVATIVES IN ORGANIC-SOLVENTS

被引：2

作者：

EBERT, C ^{[1
]}

GARDOSSI, L ^{[1
]}

LINDA, P ^{[1
]}

TAMBWE, KM ^{[1
]}

机构：

[1] UNIV LUBUMBASHI, DEPT PHYS CHEM, LUBUMBASHI, DEM REP CONGO

来源：

BIOTECHNOLOGY TECHNIQUES | 1994年 / 8卷 / 11期

关键词：

D O I：

10.1007/BF00152889

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Lipases, when covalently modified with poly(ethylene glycol), catalyse the acylation of hydrophilic substrates in organic solvents with increase in the reaction rate even in the presence of 4% water. As a further result the modified Lipoprotein lipase from Pseudomonas species acylates only amino group in serine-beta-naphthylamide.

引用

页码：811 / 816

页数：6

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