A NOVEL-APPROACH TO THE SYNTHESIS OF ENEDIYNES

被引：61

作者：

MAGRIOTIS, PA

SCOTT, ME

KIM, KD

机构：

[1] Department of Chemistry, West Virginia University, Morgantown

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 43期

关键词：

STANNYLCUPRATION; 1-PHENYLTHIO-1-ALKYNES; VINYLCOPPER-ZINC INTERMEDIATES; STANNYL ENYNES; ENEDIYNES;

D O I：

10.1016/0040-4039(91)80759-Y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for the synthesis of enediynes is described based on stannylcupration of acetylene and certain activated alkynes, in situ reaction with 1-halo-1-alkynes, iododestannylation, and Pd(0)-catalyzed coupling with terminal alkynes.

引用

页码：6085 / 6088

页数：4

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