A NOVEL-APPROACH TO THE SYNTHESIS OF ENEDIYNES

被引:61
作者
MAGRIOTIS, PA
SCOTT, ME
KIM, KD
机构
[1] Department of Chemistry, West Virginia University, Morgantown
关键词
STANNYLCUPRATION; 1-PHENYLTHIO-1-ALKYNES; VINYLCOPPER-ZINC INTERMEDIATES; STANNYL ENYNES; ENEDIYNES;
D O I
10.1016/0040-4039(91)80759-Y
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new method for the synthesis of enediynes is described based on stannylcupration of acetylene and certain activated alkynes, in situ reaction with 1-halo-1-alkynes, iododestannylation, and Pd(0)-catalyzed coupling with terminal alkynes.
引用
收藏
页码:6085 / 6088
页数:4
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