Total synthesis of (+)-pyripyropene A. A potent, orally bioavailable inhibitor of acyl-CoA:cholesterol acyltransferase

被引：72

作者：

Nagamitsu, T

Sunazuka, T

Obata, R

Tomoda, H

Tanaka, H

Harigaya, Y

Omura, S

Smith, AB

机构：

[1] UNIV PENN,MONELL CHEM SENSES CTR,DEPT CHEM,PHILADELPHIA,PA 19104

[2] UNIV PENN,RES STRUCT MATTER LAB,PHILADELPHIA,PA 19104

[3] KITASATO UNIV,KITASATO INST,BIOL FUNCT RES CTR,MINATO KU,TOKYO 108,JAPAN

[4] KITASATO UNIV,SCH PHARMACEUT SCI,MINATO KU,TOKYO 108,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 25期

关键词：

D O I：

10.1021/jo00130a005

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：8126 / 8127

页数：2

共 30 条

[1]

BELL FP, 1986, PHARM CONTROL HYPERL, P409

[2]

BILHEIMER JT, 1991, 9TH INT S ATH ROS, P94

[3] PALLADIUM-CATALYZED CARBONYLATION OF ENOL TRIFLATES - A NOVEL METHOD FOR ONE-CARBON HOMOLOGATION OF KETONES TO ALPHA,BETA-UNSATURATED CARBOXYLIC-ACID DERIVATIVES [J].

CACCHI, S ;

MORERA, E ;

ORTAR, G .

TETRAHEDRON LETTERS, 1985, 26 (08) :1109-1112

[4]

CHANG G, 1993, 206TH NAT M AM CHEM, P337

[5] PYRONE STUDIES . LINEAR ALPHA-PYRONE ROUTE TO PROTECTED BETA-POLYKETONES [J].

DOUGLAS, JL ;

MONEY, T .

CANADIAN JOURNAL OF CHEMISTRY, 1968, 46 (05) :695-&

[6] THE DIRECTED REDUCTION OF BETA-HYDROXY KETONES EMPLOYING ME4NHB(OAC)3 [J].

EVANS, DA ;

CHAPMAN, KT .

TETRAHEDRON LETTERS, 1986, 27 (49) :5939-5942

[7]

FURLENMEIER A., 1966, HELV CHIM ACTA, V49, P1591, DOI 10.1002/hlca.19660490518

[8]

HEIDER JG, 1986, PHARM CONTROL HYPERL, P423

[9] SYNTHESIS OF (+/-)-11-NOR-9-CARBOXY-DELTA-9-TETRAHYDROCANNABINOL - NEW SYNTHETIC APPROACHES TO CANNABINOIDS [J].

HUFFMAN, JW ;

ZHANG, XH ;

WU, MJ ;

JOYNER, HH ;

PENNINGTON, WT .

JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (04) :1481-1489

[10] GERI-BP001, A NEW INHIBITOR OF ACYL-COA - CHOLESTEROL ACYLTRANSFERASE PRODUCED BY ASPERGILLUS-FUMIGATUS F37 [J].

JEONG, TS ;

KIM, SU ;

KWON, BM ;

SON, KH ;

KIM, YK ;

CHOI, MU ;

BOK, SH .

TETRAHEDRON LETTERS, 1994, 35 (21) :3569-3570

← 1 2 3 →