DIELECTRIC-PROPERTIES OF THE SYSTEM BOVINE ALBUMIN-UREA-BETAINE IN AQUEOUS-SOLUTION

被引：18

作者：

BATEMAN, JB ^{[1
]}

EVANS, GF ^{[1
]}

BROWN, PR ^{[1
]}

GABRIEL, C ^{[1
]}

GRANT, EH ^{[1
]}

机构：

[1] UNIV LONDON KINGS COLL,DEPT BIOCHEM,LONDON WC2R 2LS,ENGLAND

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 1992年 / 37卷 / 01期

关键词：

D O I：

10.1088/0031-9155/37/1/012

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Urea (about 5 mol l-1) causes an approximately five-fold increase of the dielectric increment of bovine serum albumin at 20-degrees-C. The increase is reversed by betaine (about 2.5 mol l-1), or prevented if urea and betaine are added together. This result can be seen as an electric counterpart to the protective role of osmolytes which are secreted by cells and tissues subjected to various types of internal or environmental stress.

引用

页码：175 / 182

页数：8

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