SEMINAL WHITE BLOOD-CELLS AND RECURRENT ABORTION

被引：12

作者：

HILL, JA ^{[1
]}

ANDERSON, DJ ^{[1
]}

POLGAR, K ^{[1
]}

ABBOTT, AF ^{[1
]}

POLITCH, JA ^{[1
]}

机构：

[1] HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,DEPT OBSTET GYNECOL & REPROD BIOL,DIV REPROD IMMU,BOSTON,MA 02115

来源：

HUMAN REPRODUCTION | 1994年 / 9卷 / 06期

关键词：

CYTOKINES; LEUKOCYTOSPERMIA; RECURRENT ABORTIONS; SEMEN; WHITE BLOOD CELLS;

D O I：

10.1093/oxfordjournals.humrep.a138655

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The incidence of leukocytospermia (>1 million white blood cells/ml semen) and concentrations of white blood cell populations in semen from men whose partners experience unexplained recurrent spontaneous abortion by conventional testing criteria are described and compared to those of men whose partners have normal reproductive histories. Comparable seminal granulocyte and total white blood cell concentrations between groups suggest that couples with unexplained recurrent abortion do not have an abnormally high incidence of subclinical genital tract infections for which leukocytospermia could serve as a marker. However, a significantly higher prevalence of elevated CD4(+) and CD8(+) T lymphocyte concentrations in semen from men whose partners have cellular immunity to sperm antigens (i.e. produce embryotoxic factors in response to sperm antigen stimulation) warrants further investigation.

引用

页码：1180 / 1183

页数：4

共 23 条

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