3-DIFFERENT-COMPONENT [1+2+N]-ANNULATION REACTIONS - IONIC AND RADICAL CYCLIZATIONS

被引：17

作者：

POSNER, GH

ASIRVATHAM, E

HAMILL, TG

WEBB, KS

机构：

[1] Department of Chemistry, The Johns Hopkins University, Baltimore

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 07期

关键词：

D O I：

10.1021/jo00294a029

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

One-carbon-atom Michael donors are used to initiate convergent and flexible [1 + 2 + 3]-hexannulations and [1 + 2 + 2]-pentannulations in which the initial nucleophilic carbon atom terminates the reaction sequence in an ionic fashion as an electrophilic center or in a carbon-centered radical fashion as a nucleophilic center. This protocol is used to prepare regiospecifically substituted bicyclic ketones and lactones and a cis-bicyclic tetra-hydrofuran. © 1990, American Chemical Society. All rights reserved.

引用

页码：2132 / 2137

页数：6

共 55 条

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