INVITRO BINDING OF HELICOBACTER-PYLORI TO HUMAN GASTRIC MUCIN

被引：59

作者：

TZOUVELEKIS, LS

MENTIS, AF

MAKRIS, AM

SPILIADIS, C

BLACKWELL, C

WEIR, DM

机构：

[1] HIPPOCRATION HOSP, DEPT INTERNAL MED, GR-11521 ATHENS, GREECE

[2] ATHENS GEN HOSP, DEPT GASTROENTEROL, GR-11527 ATHENS, GREECE

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 11期

关键词：

D O I：

10.1128/IAI.59.11.4252-4254.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The in vitro binding of four Helicobacter pylori strains to human gastric mucin was studied with an enzyme-linked immunosorbent assay. All four strains were found to bind to purified mucin. Neuraminidase treatment and nonspecific oxidation of mucin decreased bacterial adherence to the macromolecule. Mucin preparations were also found to inhibit attachment of H. pylori to HEp-2 monolayers.

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页码：4252 / 4254

页数：3

相关论文

共 16 条

[1] GASTRIC CAMPYLOBACTER-LIKE ORGANISMS, GASTRITIS, AND PEPTIC-ULCER DISEASE [J].

BLASER, MJ .

GASTROENTEROLOGY, 1987, 93 (02) :371-383

[2] RELATION OF CAMPYLOBACTER-PYLORIDIS TO GASTRITIS AND PEPTIC-ULCER [J].

BUCK, GE ;

GOURLEY, WK ;

LEE, WK ;

SUBRAMANYAM, K ;

LATIMER, JM ;

DINUZZO, AR .

JOURNAL OF INFECTIOUS DISEASES, 1986, 153 (04) :664-669

[3] RECEPTOR-MEDIATED ADHERENCE OF CAMPYLOBACTER-PYLORI TO MOUSE Y-1 ADRENAL-CELL MONOLAYERS [J].

EVANS, DG ;

EVANS, DJ ;

GRAHAM, DY .

INFECTION AND IMMUNITY, 1989, 57 (08) :2272-2278

[4] N-ACETYLNEURAMINYLLACTOSE-BINDING FIBRILLAR HEMAGGLUTININ OF CAMPYLOBACTER-PYLORI - A PUTATIVE COLONIZATION FACTOR ANTIGEN [J].

EVANS, DG ;

EVANS, DJ ;

MOULDS, JJ ;

GRAHAM, DY .

INFECTION AND IMMUNITY, 1988, 56 (11) :2896-2906

[5] CAMPYLOBACTER-PYLORIDIS, GASTRITIS, AND PEPTIC-ULCERATION [J].

GOODWIN, CS ;

ARMSTRONG, JA ;

MARSHALL, BJ .

JOURNAL OF CLINICAL PATHOLOGY, 1986, 39 (04) :353-365

[6] MUCUS COLONIZATION AS A DETERMINANT OF PATHOGENICITY IN INTESTINAL INFECTION BY CAMPYLOBACTER-JEJUNI - A MOUSE CECAL MODEL [J].

LEE, A ;

OROURKE, JL ;

BARRINGTON, PJ ;

TRUST, TJ .

INFECTION AND IMMUNITY, 1986, 51 (02) :536-546

[7] BINDING OF YERSINIA-ENTEROCOLITICA TO RABBIT INTESTINAL BRUSH-BORDER MEMBRANES, MUCUS, AND MUCIN [J].

MANTLE, M ;

BASARABA, L ;

PEACOCK, SC ;

GALL, DG .

INFECTION AND IMMUNITY, 1989, 57 (11) :3292-3299

[8]

MENTIS A, 1990, FEMS (Federation of European Microbiological Societies) Microbiology Immunology, V64, P125, DOI 10.1111/j.1574-6968.1990.tb03511.x

[9] HEMAGGLUTINATION ACTIVITY OF CAMPYLOBACTER-PYLORI [J].

NAKAZAWA, T ;

ISHIBASHI, M ;

KONISHI, H ;

TAKEMOTO, T ;

SHIGEEDA, M ;

KOCHIYAMA, T .

INFECTION AND IMMUNITY, 1989, 57 (03) :989-991

[10] MUCINOPHILIC AND CHEMOTACTIC PROPERTIES OF PSEUDOMONAS-AERUGINOSA IN RELATION TO PULMONARY COLONIZATION IN CYSTIC-FIBROSIS [J].

NELSON, JW ;

TREDGETT, MW ;

SHEEHAN, JK ;

THORNTON, DJ ;

NOTMAN, D ;

GOVAN, JRW .

INFECTION AND IMMUNITY, 1990, 58 (06) :1489-1495