INVITRO BINDING OF HELICOBACTER-PYLORI TO HUMAN GASTRIC MUCIN

被引：59

作者：

TZOUVELEKIS, LS

MENTIS, AF

MAKRIS, AM

SPILIADIS, C

BLACKWELL, C

WEIR, DM

机构：

[1] HIPPOCRATION HOSP, DEPT INTERNAL MED, GR-11521 ATHENS, GREECE

[2] ATHENS GEN HOSP, DEPT GASTROENTEROL, GR-11527 ATHENS, GREECE

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 11期

关键词：

D O I：

10.1128/IAI.59.11.4252-4254.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The in vitro binding of four Helicobacter pylori strains to human gastric mucin was studied with an enzyme-linked immunosorbent assay. All four strains were found to bind to purified mucin. Neuraminidase treatment and nonspecific oxidation of mucin decreased bacterial adherence to the macromolecule. Mucin preparations were also found to inhibit attachment of H. pylori to HEp-2 monolayers.

引用

页码：4252 / 4254

页数：3

共 16 条

[11] CONSERVATION AND DIVERSITY OF CAMPYLOBACTER-PYLORIDIS MAJOR ANTIGENS [J].