NEW AND HIGHLY (E)-SELECTIVE SYNTHESIS OF TERMINAL 1,3-DIENE VIA 3-CARBON ELONGATION OF ALDEHYDE

被引：21

作者：

MAETA, H ^{[1
]}

SUZUKI, K ^{[1
]}

机构：

[1] KEIO UNIV,DEPT CHEM,KOHOKU KU,YOKOHAMA,KANAGAWA 223,JAPAN

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(00)61102-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthetic method of 1,3-diene by three-carbon elongation of aldehyde is described. 3-Trimethylsilyl-1-propenylzirconocene chloride (2), generated from 3-trimethylsilyl-1-propyne (1) and Cp2Zr(H)Cl, reacts with aldehyde in the presence of catalytic AgClO4 and subsequent one-pot 1,4-elimination affords 1,3-dienes in high yields with excellent (E)-selectivities.

引用

页码：5969 / 5972

页数：4

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