APHE-1 AND APHE-2, 2 NEW ANTIMICROBIAL AND CYTOTOXIC ANTIBIOTICS .2. PHYSICOCHEMICAL PROPERTIES AND STRUCTURE ELUCIDATION

被引：12

作者：

FIDALGO, ML

ARIAS, MS

SOLIVERI, J

ARIAS, ME

机构：

[1] UNIV ALCALA DE HENARES, DEPT MICROBIOL & PARASITOL, E-28871 ALCALA DE HENARES, SPAIN

[2] UNIV ALCALA DE HENARES, DEPT QUIM ORGAN, E-28871 ALALA DE HENARES, SPAIN

来源：

JOURNAL OF ANTIBIOTICS | 1992年 / 45卷 / 11期

关键词：

D O I：

10.7164/antibiotics.45.1759

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Two new pyrazolo-isoquinolinone antibiotics, APHE-1 and APHE-2, have been isolated from the culture filtrate and mycelia of Streptoverticillium griseocarneum NCIMB 40447. Molecular formulae were established as C13H12N2O for APHE-1 and C14H14N2O for APHE-2, by elemental analysis, NMR and mass spectra. 2D NMR techniques (H-1-H-1 COSY-45 and H-1-C-13 correlated spectroscopy) have been applied to establish their structures.

引用

页码：1759 / 1762

页数：4

共 9 条

[1] INVESTIGATION OF COMPLEX NETWORKS OF SPIN-SPIN COUPLING BY TWO-DIMENSIONAL NMR [J].