EFFECTS OF PEPTIDASE INHIBITORS ON THE [MET5]-ENKEPHALIN HYDROLYSIS IN ILEAL AND STRIATAL PREPARATIONS OF GUINEA-PIG - ALMOST COMPLETE PROTECTION OF DEGRADATION BY THE COMBINATION OF AMASTATIN, CAPTOPRIL AND THIORPHAN

被引：36

作者：

HIRANUMA, T ^{[1
]}

OKA, T ^{[1
]}

机构：

[1] TOKAI UNIV,SCH MED,DEPT PHARMACOL,ISEHARA,KANAGAWA 25911,JAPAN

来源：

JAPANESE JOURNAL OF PHARMACOLOGY | 1986年 / 41卷 / 04期

关键词：

D O I：

10.1254/jjp.41.437

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：437 / 446

页数：10

共 15 条

[1] THE ROLE OF BESTATIN-SENSITIVE AMINOPEPTIDASE, ANGIOTENSIN CONVERTING ENZYME AND THIORPHAN-SENSITIVE ENKEPHALINASE IN THE POTENCY OF ENKEPHALINS IN THE GUINEA-PIG ILEUM [J].

AOKI, K ;

KAJIWARA, M ;

OKA, T .

JAPANESE JOURNAL OF PHARMACOLOGY, 1984, 36 (01) :59-65

[2] THE INACTIVATION OF [MET5] ENKEPHALIN BY BESTATIN-SENSITIVE AMINOPEPTIDASE, CAPTOPRIL-SENSITIVE PEPTIDYL DIPEPTIDASE-A AND THIORPHAN-SENSITIVE ENDOPEPTIDASE-24.11 IN MOUSE VAS-DEFERENS [J].

AOKI, K ;

KAJIWARA, M ;

OKA, T .

JAPANESE JOURNAL OF PHARMACOLOGY, 1986, 40 (02) :297-302

[3] INHIBITION OF ENZYMATIC DEGRADATION OF LEU-ENKEPHALIN BY PUROMYCIN [J].

BARCLAY, RK ;

PHILLIPPS, MA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 81 (04) :1119-1123

[4]

COHEN ML, 1983, J PHARMACOL EXP THER, V224, P379

[5] CENTRAL DISTRIBUTION OF OPIOID-PEPTIDES [J].

CUELLO, AC .

BRITISH MEDICAL BULLETIN, 1983, 39 (01) :11-+

[6] PARTICIPATION OF BOTH ENKEPHALINASE AND AMINOPEPTIDASE ACTIVITIES IN THE METABOLISM OF ENDOGENOUS ENKEPHALINS [J].

DELABAUME, S ;

YI, CC ;

SCHWARTZ, JC ;

CHAILLET, P ;

MARCAISCOLLADO, H ;

COSTENTIN, J .

NEUROSCIENCE, 1983, 8 (01) :143-151

[7] ENDOPEPTIDASE-24.11 PURIFIED FROM PIG INTESTINE IS DIFFERENTLY GLYCOSYLATED FROM THAT IN KIDNEY [J].

FULCHER, IS ;

CHAPLIN, MF ;

KENNY, AJ .

BIOCHEMICAL JOURNAL, 1983, 215 (02) :317-323

[8] REGIONAL STUDIES OF CATECHOLAMINES IN RAT BRAIN .I. DISPOSITION OF [3H]NOREPINEPHRINE [3H]DOPAMINE AND [3H]DOPA IN VARIOUS REGIONS OF BRAIN [J].

GLOWINSKI, J ;

IVERSEN, LL .

JOURNAL OF NEUROCHEMISTRY, 1966, 13 (08) :655-+

[9] 2 DISTINCT ENKEPHALINASES - SOLUBILIZATION, PARTIAL-PURIFICATION AND SEPARATION FROM ANGIOTENSIN CONVERTING ENZYME [J].

GORENSTEIN, C ;

SNYDER, SH .

LIFE SCIENCES, 1979, 25 (24-2) :2065-2070

[10]

Hartsuck J. A., 1971, ENZYMES, V3, P1

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