MOTOR-NERVE BIOPSY IN SEVERE GUILLAIN-BARRE-SYNDROME

被引:50
作者
HALL, SM
HUGHES, RAC
ATKINSON, PF
MCCOLL, I
GALE, A
机构
[1] GUYS HOSP,UNITED MED & DENT SCH,DEPT SURG,LONDON SE1 9RT,ENGLAND
[2] LUTON & DUNSTABLE HOSP,LUTON LU4 0DZ,BEDS,ENGLAND
关键词
D O I
10.1002/ana.410310416
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We undertook a biopsy of a terminal branch of the musculocutaneous nerve in a man with severe Guillain-Barre syndrome and very small distally evoked action potentials. The biopsy showed pronounced subperineurial edema, macrophage infiltration, and many axons that had been completely demyelinated, some associated with intratubal macrophages. The biopsy unequivocally identified the pathological process as primary demyelination, not axonal degeneration, and was more informative than previous reports of sural nerve biopsies in patients with Guillain-Barre syndrome.
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页码:441 / 444
页数:4
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