THYMIDYLATE SYNTHETASE-POSITIVE AND SYNTHETASE-NEGATIVE MURINE MAMMARY FM3A CARCINOMA-CELLS AS A USEFUL SYSTEM FOR DETECTING THYMIDYLATE SYNTHETASE INHIBITORS

被引：6

作者：

BALZARINI, J ^{[1
]}

DECLERCQ, E ^{[1
]}

AYUSAWA, D ^{[1
]}

SENO, T ^{[1
]}

机构：

[1] SAITAMA CANC CTR,RES INST,DEPT IMMUNOL & VIROL,INA,SAITAMA 367,JAPAN

来源：

FEBS LETTERS | 1984年 / 173卷 / 01期

关键词：

D O I：

10.1016/0014-5793(84)81052-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：227 / 232

页数：6

共 36 条

[1] SELECTION OF MAMMALIAN THYMIDINE AUXOTROPHIC CELL MUTANTS DEFECTIVE IN THYMIDYLATE SYNTHASE BY THEIR REDUCED SENSITIVITY TO METHOTREXATE
AYUSAWA, D
KOYAMA, H
IWATA, K
SENO, T
[J]. SOMATIC CELL GENETICS, 1981, 7 (05): : 523 - 534
[2] SINGLE-STEP SELECTION OF MOUSE FM3A CELL MUTANTS DEFECTIVE IN THYMIDYLATE SYNTHETASE
AYUSAWA, D
KOYAMA, H
IWATA, K
SENO, T
[J]. SOMATIC CELL GENETICS, 1980, 6 (02): : 261 - 270
[3] THYMIDYLATE SYNTHETASE-DEFICIENT MOUSE FM3A MAMMARY-CARCINOMA CELL-LINE AS A TOOL FOR STUDYING THE THYMIDINE SALVAGE PATHWAY AND THE INCORPORATION OF THYMIDINE ANALOGS INTO HOST-CELL DNA
BALZARINI, J
DECLERCQ, E
AYUSAWA, D
SENO, T
[J]. BIOCHEMICAL JOURNAL, 1984, 217 (01) : 245 - 252
[4] STRATEGIES FOR THE MEASUREMENT OF THE INHIBITORY EFFECTS OF THYMIDINE ANALOGS ON THE ACTIVITY OF THYMIDYLATE SYNTHASE IN INTACT MURINE LEUKEMIA L1210-CELLS
BALZARINI, J
DECLERCQ, E
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1984, 785 (1-2) : 36 - 45
[5] ROLE OF THYMIDINE KINASE IN THE INHIBITORY ACTIVITY OF 5-SUBSTITUTED-2'-DEOXYURIDINES ON THE GROWTH OF HUMAN AND MURINE TUMOR-CELL LINES
BALZARINI, J
DECLERCQ, E
TORRENCE, PF
MERTES, MP
PARK, JS
SCHMIDT, CL
SHUGAR, D
BARR, PJ
JONES, AS
VERHELST, G
WALKER, RT
[J]. BIOCHEMICAL PHARMACOLOGY, 1982, 31 (06) : 1089 - 1095
[6] 5-SUBSTITUTED 2'-DEOXYURIDINES - CORRELATION BETWEEN INHIBITION OF TUMOR-CELL GROWTH AND INHIBITION OF THYMIDINE KINASE AND THYMIDYLATE SYNTHETASE
BALZARINI, J
DECLERCQ, E
MERTES, MP
SHUGAR, D
TORRENCE, PF
[J]. BIOCHEMICAL PHARMACOLOGY, 1982, 31 (22) : 3673 - 3682
[7] SYNTHESIS OF NUCLEOSIDES DERIVED FROM 5-ETHYNYLURACIL AND 5-ETHYNYL-CYTOSINE
BARR, PJ
JONES, AS
SERAFINOWSKI, P
WALKER, RT
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1978, (10): : 1263 - 1267
[8] BLAKLEY RL, 1963, J BIOL CHEM, V238, P2113
[9] THYMIDYLATE SYNTHETASE - TARGET ENZYME IN CANCER CHEMOTHERAPY
DANENBERG, PV
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1977, 473 (02) : 73 - 92
[10] ANTIVIRAL ACTIVITY OF 5-ETHYL PYRIMIDINE DEOXYNUCLEOSIDES
DECLERCQ, E
SHUGAR, D
[J]. BIOCHEMICAL PHARMACOLOGY, 1975, 24 (10) : 1073 - 1078

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