A PLACEBO-CONTROLLED STUDY OF LACTOBACILLUS GG COLONIZATION IN ONE-TO-3-YEAR-OLD PERUVIAN CHILDREN - SHORT REPORT

被引：19

作者：

SHEEN, P

OBERHELMAN, RA

GILMAN, RH

CABRERA, L

VERASTEGUI, M

MADICO, G

机构：

[1] TULANE UNIV,SCH PUBL HLTH & TROP MED,DEPT TROP MED,NEW ORLEANS,LA 70112

[2] JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH,DEPT INT HLTH,BALTIMORE,MD

[3] ASOCIAC BENEFICA PRISMA,PROYECTOS INFORMAT SALUD MED & AGR,LIMA,PERU

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 1995年 / 52卷 / 05期

关键词：

D O I：

10.4269/ajtmh.1995.52.389

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A pilot, placebo-controlled study conducted in Peruvian toddlers in a periurban shanty-town community demonstrates that 1) a simple fluorescent antibody test performed on bacteria from colonies grown on solid culture media can be used as a presumptive screening tool for Lactobacillus GG, 2) Lactobacillus GG powder sprinkled on flavored gelatin as a nutritional supplement is well-accepted by infants and mothers in this population, and 3) daily doses of Lactobacillus GG result in efficient colonization of the gastrointestinal tract of Peruvian infants. This study demonstrates that Lactobacillus GG should be evaluated as an adjunct for diarrhea control programs at the community level as well as in hospital-based settings.

引用

页码：389 / 392

页数：4

共 11 条

[1] SURVIVAL OF LACTOBACILLUS SPECIES (STRAIN GG) IN HUMAN GASTROINTESTINAL-TRACT [J].