5 NEW CYTOTOXIC T-CELL EPITOPES IDENTIFIED WITHIN EPSTEIN-BARR-VIRUS NUCLEAR ANTIGEN-3

被引：86

作者：

BURROWS, SR

GARDNER, J

KHANNA, R

STEWARD, T

MOSS, DJ

RODDA, S

SUHRBIER, A

机构：

[1] QUEENSLAND INST MED RES,BANCROFT CTR,BRISBANE,QLD 4029,AUSTRALIA

[2] CHIRON MIMOTOPES PTY LTD,CLAYTON,VIC 3168,AUSTRALIA

来源：

JOURNAL OF GENERAL VIROLOGY | 1994年 / 75卷

基金：

英国惠康基金;

关键词：

D O I：

10.1099/0022-1317-75-9-2489

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Epstein-Barr virus (EBV) CD8(+) cytotoxic T lymphocyte (CTL) epitopes are currently being considered for inclusion into subunit vaccines. Here we describe the characterization of five new CTL epitopes within EBV nuclear antigen 3 (EBNA3), confirming EBNA3 as a major target for CTL recognition.

引用

页码：2489 / 2493

页数：5

共 28 条

[21] A MALARIA T-CELL EPITOPE RECOGNIZED IN ASSOCIATION WITH MOST MOUSE AND HUMAN MHC CLASS-II MOLECULES
SINIGAGLIA, F
GUTTINGER, M
KILGUS, J
DORAN, DM
MATILE, H
ETLINGER, H
TRZECIAK, A
GILLESSEN, D
PINK, JRL
[J]. NATURE, 1988, 336 (6201) : 778 - 780
[22] SUHRBIER A, 1993, IMMUNOLOGY, V79, P171
[23] EBNA-5, AN EPSTEIN-BARR VIRUS-ENCODED NUCLEAR ANTIGEN, BINDS TO THE RETINOBLASTOMA AND P53 PROTEINS
SZEKELY, L
SELIVANOVA, G
MAGNUSSON, KP
KLEIN, G
WIMAN, KG
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (12) : 5455 - 5459
[24] SYNTHESIS OF PEPTIDE ANALOGS USING THE MULTIPIN PEPTIDE-SYNTHESIS METHOD
VALERIO, RM
BENSTEAD, M
BRAY, AM
CAMPBELL, RA
MAEJI, NJ
[J]. ANALYTICAL BIOCHEMISTRY, 1991, 197 (01) : 168 - 177
[25] SITE-SPECIFIC MUTAGENESIS OF THE HUMAN INTERLEUKIN-2 GENE - STRUCTURE-FUNCTION ANALYSIS OF THE CYSTEINE RESIDUES
WANG, A
LU, SD
MARK, DF
[J]. SCIENCE, 1984, 224 (4656) : 1431 - 1433
[26] AN EBV MEMBRANE-PROTEIN EXPRESSED IN IMMORTALIZED LYMPHOCYTES TRANSFORMS ESTABLISHED RODENT CELLS
WANG, D
LIEBOWITZ, D
KIEFF, E
[J]. CELL, 1985, 43 (03) : 831 - 840
[27] WIDMANN C, 1991, J IMMUNOL, V147, P3745
[28] AN HLA-A11-SPECIFIC MOTIF IN NONAMER PEPTIDES DERIVED FROM VIRAL AND CELLULAR PROTEINS
ZHANG, QJ
GAVIOLI, R
KLEIN, G
MASUCCI, MG
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (06) : 2217 - 2221

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