EFFICIENT TOTAL SYNTHESIS OF RACEMIC AND OPTICALLY-ACTIVE CYCLOBUT-A AND SIMPLE ANALOGS

被引：43

作者：

JUNG, ME

SLEDESKI, AW

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 07期

关键词：

D O I：

10.1039/c39930000589

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Rapid synthesis of the potent antiviral agent, cyclobut-A, la, from the inexpensive starting materials maleic anhydride and acetylene, in both racemic and optically active forms, is described; the route also allows for the preparation of several hydroxylated and keto analogues in good overall yield.

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页码：589 / 591

页数：3

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