DALDA (H-TYR-D-ARG-PHE-LYS-NH2), A POTENT MU-OPIOID PEPTIDE AGONIST, AFFECTS VARIOUS PATTERNS OF LOCOMOTOR ACTIVITIES

被引：14

作者：

MEYER, ME

MCLAURIN, BI

MEYER, ME

机构：

[1] Department of Psychology, University of Florida, Gainesville

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1995年 / 51卷 / 01期

关键词：

MU-OPIOID PEPTIDE AGONISTS; DALDA; LOCOMOTOR ACTIVITY; REARING; LINEAR LOCOMOTION; STEREOTYPY;

D O I：

10.1016/0091-3057(94)00308-6

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The central effects of mu-opioid receptor agonist DALDA (ICV 0.00, 0.1, or 1.0 mu g) were investigated in rats for 120 min on activity monitors. The durations in seconds of horizontal. movement time, rearing time, and stereotypy time were measured during 12 consecutive 10-min time blocks. DALDA (ICV, 0.1 and 1.0 mu g) resulted in biphasic effects, inhibition followed by activation for horizontal movement, rearing, and stereotypy times.

引用

页码：149 / 151

页数：3

共 11 条

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