共 30 条
LONG-TERM RETENTION OF IMPLICIT LEARNING IN HUNTINGTONS-DISEASE
被引:20
作者:
BYLSMA, FW
REBOK, GW
BRANDT, J
机构:
[1] Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University, Baltimore, MD
关键词:
D O I:
10.1016/0028-3932(91)90035-7
中图分类号:
B84 [心理学];
C [社会科学总论];
Q98 [人类学];
学科分类号:
03 ;
0303 ;
030303 ;
04 ;
0402 ;
摘要:
Implicit learning was examined in 15 Huntington's disease (HD) patients and 15 control subjects (NC) using a semantic decision-making task. HD patients demonstrated only slightly reduced priming; like NC subjects, their decision times decreased over repeated presentations, though to a somewhat lesser degree. On explicit recognition testing, the HD group made significantly more false positive errors than did the control group, suggesting an impairment of effortful retrieval. The groups displayed equivalent retention of implicitly learned material after 6 months. The striatal neuronal loss of early Huntington's disease does not markedly affect priming or retention of primed stimuli, but may alter explicit memory judgements.
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页码:1213 / 1221
页数:9
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