THE DESIGN AND SYNTHESIS OF BONE-ACTIVE PHOSPHINIC ACID ANALOGS .1. THE PYRIDYLAMINOMETHANE PHOSPHONALKYLPHOSPHINATES

被引：34

作者：

EBETINO, FH

JAMIESON, LA

机构：

[1] Norwich Eaton Pharmaceuticals, A Procter and Gamble Company, Norwich, 13815

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1990年 / 51卷 / 1-4期

关键词：

D O I：

10.1080/10426509008040673

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The bisDhosDhonic acids and their salts. the bisnho&Dhonates. have been tt-” subject of study by a number of research groups for their marked ability to modulate bone metabolism. From a recent study of phosphinic acid isosteres, we have designed a novel related class of bone active agents, the pyridylaminomethane phosphonoalkylposphinates I. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：23 / 26

页数：4

共 15 条

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