SUCCESSFUL TREATMENT OF ANTIMONY-RESISTANT VISCERAL LEISHMANIASIS WITH LIPOSOMAL AMPHOTERICIN-B IN PATIENTS INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS

被引：64

作者：

TORRECISNEROS, J

VILLANUEVA, JL

KINDELAN, JM

JURADO, R

SANCHEZGUIJO, P

机构：

[1] Infectious Diseases Unit, Department of Internal Medicine, Hospital Regional Universitario Reina Sofía, Cordoba

来源：

CLINICAL INFECTIOUS DISEASES | 1993年 / 17卷 / 04期

关键词：

D O I：

10.1093/clinids/17.4.625

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We describe two cases of visceral leishmaniasis in patients infected with human immunodeficiency virus (HIV); both cases were resistant to antimony compounds but were cured with liposomal amphotericin B, with no significant toxicity. A review of the previous reported cases of antimony-resistant visceral leishmaniasis in HIV-infected patients confirmed the effectiveness of treatment with liposomal amphotericin B, which directly targets infected macrophages and reaches high levels in plasma and tissue.

引用

页码：625 / 627

页数：3

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